- Tilda Swinton - Elizabeth Abbott
- Faune Chambers Watkins - Dorothy Baker
- Donna DuPlantier - Blanche Devereux
- Jacob Tolano - Martin Gateau
- Earl Maddox - Man at Train Station
- Ed Metzger - Teddy Roosevelt
- Danny Vinson - Priest Giving Last Rites
- David Jensen - Doctor at Benjamin's Birth
- Joeanna Sayler - Caroline Button
- Fiona Hale - Mrs. Hollister
- Patrick Thomas O'Brien - Dr. Rose
- Marion Zinser - Mrs. Horton
- Peter Donald Badalamenti II - Benjamin 1928-31
- Danny Nelson - General Winston
- Paula Gray - Sybil Wagner
- Lance E. Nichols - Preacher
- Rampai Mohadi - Ngunda Oti
- Troi Bechet - Filamena Gilea
- Elle Fanning - Daisy Age 7
- Ted Manson - Mr. Daws
- Clay Cullen - Young Mr. Daws
- Edith Ivey - Mrs. Maple
- Robert Towers - Benjamin 1932-34
- Sonya Leslie - Daisy's Nurse
- Yasmine Abriel - Prostitute with Benjamin
- Madisen Beaty - Daisy Age 10
- Tom Everett - Benjamin 1935-37
- Don Creech - Prentiss Mayes
- Christopher DesRoches - Rick Brody
- Joshua Desroches - Vic Brody
- Richmond Arquette - John Grimm
- Josh Stewart - Pleasant Curtis
- Ilia Volok - Russian Interpreter
- David Ross Paterson - Walter Abbott
- Taren Cunningham - Young Elizabeth Abbott
- Myrton Running Wolf - Dennis Smith
- Stephen Monroe Taylor - Sailor
- Devyn A. Tyler - Queenie's Daughter Age 14
- Adrian Armas - David
- Wilbur Fitzgerald - TV Reporter
- Ashley Nolan - Woman Doctor
- Louis Herthum - Man at Caroline's Party
- Katta Hules - Caroline Age 12
- Rus Blackwell - Robert Williams
- Joel Bissonnette - David Hernandez
- Deneen Tyler - Queenie's Daughter Age 40
- Spencer Daniels - Benjamin Age 12
- Chandler Canterbury - Benjamin Age 8
- Charles Henry Wyson - Benjamin Age 6
- Jessica Cropper - Featured Dancer
- Katherine Crockett - Featured Dancer
- Bianca Roe - Ballerina Who Ties Up Shoelace (uncredited)
- Emma Degerstedt - Ballet Dancer (uncredited)
- Megan Brown - Woman Kissing Benjamin (uncredited)
- Clay Chamberlin - The Grumpy Sailor (uncredited)
- Leslie Augustine - Ballet Dancer (uncredited)
- Blake Balu - Restaurant Patron (uncredited)
- Aliane Baquerot - Ballet Dancer (uncredited)
- Brett Beoubay - 1918 Police Officer (uncredited)
- Allen Boudreaux - Teddy Roosevelt's Secret Service Agent (uncredited)
- Eve Brent - Old Woman (uncredited)
- David E. Brown - U.S. Lieutenant (uncredited)
- Jake Carpenter - Sailor (uncredited)
- Walter Delmar - Ballet Dancer (uncredited)
- Louis Dupuy - Taxi Driver (uncredited)
- Marian Filali - Hospital Receptionist (uncredited)
- Ron Flagge - Bartender (uncredited)
- Joe Fontana - Shrimper (uncredited)
- Garrett Forbes - Ballet Dancer (uncredited)
- Tiffany Forest - Girl on Street (uncredited)
- Debby Gaudet - Restaurant Patron (uncredited)
- Simone-Elise Girard - Parisian Woman (uncredited)
- Geraldine Glenn - Family Member (uncredited)
- Zuri Goldman - Ballet Dancer (uncredited)
- Malerie Grady - Ballet Dancer (uncredited)
- Bob Harter - Man Who Buys Button House (uncredited)
- Rhonda Huete - Button Factory Worker (uncredited)
- Grant James - Joking Old Man (uncredited)
- Christopher Karl Johnson - Medical Officer on Liberty Ship (uncredited)
- Shiloh Jolie - Caroline as Baby (uncredited)
- Spencer Kayden - Ballet Dancer (uncredited)
- Jonathan Lane - Usher at Theater (uncredited)
- Shane LeCocq - Dancer (uncredited)
- Kevin Lorio - Streetcar Driver (uncredited)
- Audrey Lynn - 1920's Woman Strolling by Window (uncredited)
- Angelina McCoy - Ballet Dancer (uncredited)
- Harlon Miller - Soldier (uncredited)
- Valeska Miller - Ballet Dancer (uncredited)
- Jay Oliver - Nolan House Resident (uncredited)
- Antonia Putiloff - J. Meranda (voice) (uncredited)
- Sean Ross - Russian Soldier (uncredited)
- Ross Rouillier - 1918 U.S. Lieutenant (uncredited)
- Robert W. Savina - Man in Rowboat (uncredited)
- Andy Sims - Man in Wheelchair (uncredited)
- Chaz Smith - Dock Worker (uncredited)
- Logan Douglas Smith - Neighbor / Son of Nursing Home Elder (uncredited)
- Terry Lee Smith - Rower (uncredited)
- Lauren Swinney - Mrs. Carter (uncredited)
- Dennis Thomas IV - Grave Digger (uncredited)
- Michel Thériault - Taxi Driver (uncredited)
- Yvette Tucker - Carousel Dancer (uncredited)
- Gelsey Weiss - Dancer (uncredited)
- Autumn Withers - Dancer (uncredited)
- Michael Wozniak - World War I Officer (uncredited)
- David Fincher
- Tarsem Singh
- Sharron Reynolds-Enriquez
- Allen Kupetsky
- Robin Swicord
- F. Scott Fitzgerald
- Kathleen Kennedy
- Frank Marshall
- Ceán Chaffin
- Laray Mayfield
- Andrea Kenyon
- William Doyle
- Alexandre Desplat
- Ren Klyce
- Ren Klyce
- Ren Klyce
- Doc Kane
- Peter Gleaves
Capítulo disponible en las siguientes plataformas:
