- Livio Lorenzon - Baker
- Sandro Scarchilli - Tuco Henchman
- Benito Stefanelli - Member of Angel Eyes' Gang
- Angelo Novi - Monk
- Antonio Casas - Stevens
- Aldo Sambrell - Member of Angel Eyes' Gang
- Al Mulock - One-Armed Bounty Hunter
- Sergio Mendizábal - Blonde Bounty Hunter
- Antonio Molino Rojo - Captain Harper
- Lorenzo Robledo - Clem
- Mario Brega - Corporal Wallace
- Chelo Alonso - Stevens' Wife (uncredited)
- Fortunato Arena - 1st Sombrero Onlooker at Tuco's 1st Hanging (uncredited)
- Román Ariznavarreta - Bounty Hunter (uncredited)
- Silvana Bacci - Mexican Woman with Blondie (uncredited)
- Joseph Bradley - Old Soldier (uncredited)
- Frank Braña - Bounty Hunter #2 (uncredited)
- Amerigo Castrighella - 2nd Sombrero Onlooker at Tuco's 1st Hanging (uncredited)
- Saturno Cerra - Bounty Hunter (uncredited)
- William Conroy - Confederate Soldier (uncredited)
- Axel Darna - Dying Confederate Soldier (uncredited)
- Tony Di Mitri - Deputy (uncredited)
- Gianni Di Segni - Deputy at 1st Hanging (uncredited)
- Alberigo Donadeo - Spectator Before Hanging (uncredited)
- Attilio Dottesio - 3rd Sombrero Onlooker at Tuco's 1st Hanging (uncredited)
- Luis Fernández de Eribe - Soldier Coat (uncredited)
- Veriano Ginesi - Bald Onlooker at Tuco's 1st Hanging (uncredited)
- Jesús Guzmán - Pardue the Hotel Owner (uncredited)
- Víctor Israel - Sergeant at Confederate Fort (uncredited)
- Nazzareno Natale - Mexican Bounty Hunter (uncredited)
- Ricardo Palacios - Barista a Socorro (uncredited)
- Antonio Palombi - Old Sergeant (uncredited)
- Romano Puppo - Member of Angel Eyes' Gang (uncredited)
- Antoñito Ruiz - Stevens' Youngest Son (uncredited)
- Aysanoa Runachagua - Pistolero Recruited by Tuco in the Cave (uncredited)
- Enrique Santiago - Mexican Bounty Hunter (uncredited)
- José Terrón - Thomas 'Shorty' Larson (uncredited)
- Franco Tocci - Union Soldier with Cigar (uncredited)
- Antonio Montoya - Mexican Bounty Hunter (uncredited)
- Sergio Leone
- Giancarlo Santi
- Fabrizio Gianni
- Serena Canevari
- Sergio Leone
- Sergio Leone
- Age
- Scarpelli
- Mickey Knox
- Gray Frederickson
- José Antonio Pérez Giner
- Antonio Palombi
- Ennio Morricone
- Alessandro Alessandroni
- Alessandro Alessandroni
- Bruno Nicolai
- Franco De Gemini
- Vittorio De Sisti
Clint Eastwood hace el papel de Blondie.
Eli Wallach hace el papel de Tuco Ramirez.
Lee Van Cleef hace el papel de Sentenza / Angel Eyes.
Aldo Giuffrè interpreta a Alcoholic Union Captain en la película.
Luigi Pistilli interpreta a Father Pablo Ramirez en la película.
Rada Rassimov hace el papel de Maria.
Enzo Petito interpreta a Storekeeper en la película.
Claudio Scarchilli interpreta a Tuco Henchman en la película.
Antonio Casale hace el papel de Bill Carson / Jackson.
Livio Lorenzon interpreta a Baker en la película.
Sandro Scarchilli hace el papel de Tuco Henchman.
Benito Stefanelli hace el papel de Member of Angel Eyes' Gang.
Angelo Novi interpreta a Monk en la película.
Antonio Casas interpreta a Stevens en la película.
Aldo Sambrell hace el papel de Member of Angel Eyes' Gang.
Al Mulock interpreta a One-Armed Bounty Hunter en la película.
Sergio Mendizábal hace el papel de Blonde Bounty Hunter.
Antonio Molino Rojo hace el papel de Captain Harper.
Lorenzo Robledo interpreta a Clem en la película.
Mario Brega hace el papel de Corporal Wallace.
Chelo Alonso interpreta a Stevens' Wife (uncredited) en la película.
Fortunato Arena hace el papel de 1st Sombrero Onlooker at Tuco's 1st Hanging (uncredited).
Román Ariznavarreta hace el papel de Bounty Hunter (uncredited).
Silvana Bacci interpreta a Mexican Woman with Blondie (uncredited) en la película.
Joseph Bradley hace el papel de Old Soldier (uncredited).
Frank Braña hace el papel de Bounty Hunter #2 (uncredited).
Amerigo Castrighella interpreta a 2nd Sombrero Onlooker at Tuco's 1st Hanging (uncredited) en la película.
Saturno Cerra interpreta a Bounty Hunter (uncredited) en la película.
William Conroy hace el papel de Confederate Soldier (uncredited).
Axel Darna interpreta a Dying Confederate Soldier (uncredited) en la película.
Tony Di Mitri interpreta a Deputy (uncredited) en la película.
Gianni Di Segni interpreta a Deputy at 1st Hanging (uncredited) en la película.
Alberigo Donadeo hace el papel de Spectator Before Hanging (uncredited).
Attilio Dottesio hace el papel de 3rd Sombrero Onlooker at Tuco's 1st Hanging (uncredited).
Luis Fernández de Eribe interpreta a Soldier Coat (uncredited) en la película.
Veriano Ginesi interpreta a Bald Onlooker at Tuco's 1st Hanging (uncredited) en la película.
Jesús Guzmán interpreta a Pardue the Hotel Owner (uncredited) en la película.
Víctor Israel interpreta a Sergeant at Confederate Fort (uncredited) en la película.
Nazzareno Natale hace el papel de Mexican Bounty Hunter (uncredited).
Ricardo Palacios hace el papel de Barista a Socorro (uncredited).
Antonio Palombi interpreta a Old Sergeant (uncredited) en la película.
Romano Puppo interpreta a Member of Angel Eyes' Gang (uncredited) en la película.
Antoñito Ruiz hace el papel de Stevens' Youngest Son (uncredited).
Aysanoa Runachagua interpreta a Pistolero Recruited by Tuco in the Cave (uncredited) en la película.
Enrique Santiago hace el papel de Mexican Bounty Hunter (uncredited).
José Terrón interpreta a Thomas 'Shorty' Larson (uncredited) en la película.
Franco Tocci hace el papel de Union Soldier with Cigar (uncredited).
Antonio Montoya interpreta a Mexican Bounty Hunter (uncredited) en la película.
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