- Roland Griffiths - Himself - Behavioral Pharmocologist
- Charles Grob - Himself - Psychiatrist
- Kathleen Harrison - Herself - Ethnobotanist
- Terence McKenna - Himself - Writer & Cultural Commentator (archive footage)
- Erik Davis - Himself - Writer
- Graham Hancock - Himself - Writer
- James Kent - Himself - Writer
- Dennis J. McKenna - Himself - Ethnopharmacologist
- Ralph Metzner - Himself - Psychologist
- Christian Meuli - Himself - DMT Volunteer, Family Physician
- Jeremy Narby - Himself - Anthropologist
- Andrew Newberg - Himself - Radiologist
- David Nichols - Himself - Medicinal Chemist
- Daniel Pinchbeck - Himself - Writer
- Douglas Rushkoff - Himself - Writer
- Spiros Antonopoulos - Himself - DMT Volunteer, Yoga Student
- Leanna Standish - Herself - Naturopathic Physician
- Andrew Stone - Himself - DMT Volunteer, Software Developer
- Rick Strassman - Himself - Psychiatrist
- Robert Weisz - Himself - DMT Volunteer, Clinical Psychiatrist
- Ricardo Amaringo - Himself
- Alvin Joseph - Himself
- Jon Levin - Himself
- Aja Loux - Herself
- José Pineda Vargas - Himself
- Jordan Phillips - Herself
- Jose Plaza - Himself
- Mitch Schultz - Himself
- Rob Velez - Himself
- Fermin Quintuna - Himself
- Ede Frecska - Himself - Psychopharmacologist
- Mitch Schultz
- Mitch Schultz
- Rick Strassman
- Mitch Schultz
- Rick Strassman
- Kerri Smeltzer
Capítulo disponible en las siguientes plataformas: