- Cosimo Fusco - Father Simeon
- Victor Alfieri - Lieutenant Valenti
- Curt Lowens - Cardinal Ebner
- Bob Yerkes - Cardinal Guidera
- Marc Fiorini - Cardinal Baggia
- Carmen Argenziano - Father Silvano Bentivoglio
- Howard Mungo - Cardinal Yoruba
- Rance Howard - Cardinal Beck
- Steve Franken - Cardinal Colbert
- Gino Conforti - Cardinal Pugini
- Elya Baskin - Cardinal Petrov
- Thomas Morris - Urs Weber
- Jonas Fisch - Adrian Bachman
- August Wittgenstein - Swiss Guardsman
- Ben Bela Böhm - Swiss Guardsman
- Jeffrey Boehm - Swiss Guard Blue
- Steve Kehela - American Reporter
- Ursula Brooks - BBC Reporter
- Rashmi - British Reporter
- Yan Cui - Chinese Reporter
- Fritz Michel - French Reporter
- Maria Cristina Heller - Italian Reporter
- Rafael Petardi - Italian Reporter
- Yesenia Adame - Mexican Reporter
- Kristof Konrad - Polish Reporter
- Masasa Moyo - South African Reporter
- Ed Francis Martin - South American Reporter
- Cheryl Howard - CERN Scientist
- Endre Hules - CERN Scientist
- Norbert Weisser - CERN Scientist
- Vanna Salviati - Protester
- Raffi Di Blasio - Protester
- Todd Schneider - Carabinieri
- Rocco Passafaro - Carabinieri
- Emanuele Secci - Carabinieri
- Anna Katarina - Docent
- James Ritz - Tourist
- Jose David Acevedo - Italian Police (uncredited)
- Roy Allen III - Cardinal (uncredited)
- Victor of Aquitaine - Vatican Choir Member (uncredited)
- Michael Ark - CNN Reporter (uncredited)
- John Jason Bailey - Swiss Guard Blue (uncredited)
- Jerred Berg - Stem Cell Protestor #2 (uncredited)
- Sally Berman - Vatican Square Singer (uncredited)
- Yuki Bird - Scientist (uncredited)
- Anthony Bonaventura - Vatican Police (uncredited)
- Ciara Bravo - Italian Girl (uncredited)
- Michael Patrick Breen - Ukrainian General (uncredited)
- Aidan Bristow - Conclave Priest #1 (uncredited)
- Christopher Casa - Tourist (uncredited)
- Patrick Casa - Choirboy / Tourist (uncredited)
- Pasquale Cassalia - Rai Reporter (uncredited)
- Jimmy Clabots - Vatican Choir Member (uncredited)
- Austin Michael Coleman - Young Funeral Mourner (uncredited)
- Robert Corvin - U.S. Army General (uncredited)
- Gina D'Acciaro - Vatican Square Singer (uncredited)
- John Dardenne - Swiss Guard Multicolor (uncredited)
- William "Will" Daubert - Priest (uncredited)
- Vincent De Paul - Vatican Pall Bearer (uncredited)
- Norman Deesing - Italian Mourner (uncredited)
- Angelique Deuitch - Tourist (uncredited)
- Paul DiVito - Priest (uncredited)
- Brant Dorman - Swiss Guard Blue (uncredited)
- Jonn Faircrest - Papal Photographer (uncredited)
- Les Feltmate - Priest (uncredited)
- Amanda Jane Fleming - Tourist (uncredited)
- David Fletcher - Protestor #3 (uncredited)
- Gregory George Frank - Protester (uncredited)
- Nancy Gassner-Clayton - Vatican Square Singer (uncredited)
- Justin Giddings - Vatican Choir Member (uncredited)
- Alan Gray - Greek Patriarch Priest (uncredited)
- Marco Greco - Fireman (uncredited)
- Roger Groh - Good Bishop (uncredited)
- Nancy Guerriero - Vatican Nun (uncredited)
- Martin Harris - Polish Reporter (uncredited)
- Miriam Harris - Mourner (uncredited)
- David Hill - Pantheon Tourist (uncredited)
- Brett Hunt - Vatican Priest (uncredited)
- Marco Infante - Italian Mourner (uncredited)
- Christopher Karl Johnson - Cardinal (uncredited)
- Dave Johnson - Press Photographer (uncredited)
- Gina Juliet - Vatican Square Singer (uncredited)
- Slim Khezri - Vatican Square Gypsy (uncredited)
- Sophiah Koikas - Tourist (uncredited)
- Michael Laren - Vatican Choir Singer (uncredited)
- Adrian Lee - Vatican Square Soloist (uncredited)
- David Michael Lewin - Mourner (uncredited)
- Maynor Lopez - Carabinieri (uncredited)
- Jon Lucero - Vatican Police Officer (uncredited)
- Eder López - Italian Citizen (uncredited)
- Julie Mabry - Protester in Vatican (uncredited)
- Les Mahoney - Hip Priest (uncredited)
- Gary Mandarino - Mourner (uncredited)
- Albert Marrero Jr. - News Camerman (uncredited)
- Sandra McCurdy - Italian Tourist (uncredited)
- Anthony Molinari - Vatican Guard (uncredited)
- Mary E. Morales - Vatican Square Soloist (uncredited)
- Sauvion Morkunas - Flag-bearer (uncredited)
- Manuel Nardi - Priest (Mr. Grey's Men) (uncredited)
- Sarita Ospina - Reporter (uncredited)
- Dale Pavinski - Carabinieri Captain (uncredited)
- David Pearl - Priest (uncredited)
- Jarrod Robbins - Swiss Guardsman (uncredited)
- Bertrand Roberson Jr. - Tourist (uncredited)
- John Robert - Tourist with Hat (uncredited)
- Franklin Ruehl - Mourner (uncredited)
- Kelly Ryan - Protestor #4 (uncredited)
- Dylan Saccoccio - Carabinieri (uncredited)
- Frank Scozzari - Vatican Police Officer (uncredited)
- James Seaman - Costudi (uncredited)
- Keith Shawn - Vatican Tourist (uncredited)
- Jutta Speidel - Woman (uncredited)
- Matthew Thane - Italian Visitor (uncredited)
- Nico Toffoli - Carabieniere Riot (uncredited)
- James Tumminia - Vatican Priest (uncredited)
- Julian Vada - Carabinieri (uncredited)
- Ryan Van de Kamp Buchanan - The Swiss Guard (uncredited)
- Ernie Ventry - Gypsy in Square (uncredited)
- Shannon Watson - Swiss Guard (uncredited)
- Jon Morgan Woodward - The American with the Sign (uncredited)
- Alfred Molina - Narrator (voice)
- Ron Howard
- Todd Hallowell
- William M. Connor
- Samantha C. Kirkeby
- Simonetta Valentini
- Inti Carboni
- David Koepp
- Akiva Goldsman
- Dan Brown
- Brian Grazer
- Janet Hirshenson
- Jane Jenkins
- Ron Howard
- Todd Hallowell
- Dan Brown
- Hans Zimmer
- Kevin Kaska
- Gary A. Hecker
- James Matheny
- Angelo Bonanni
- Rickley W. Dumm
Tom Hanks hace el papel de Robert Langdon.
Ewan McGregor hace el papel de Camerlengo Patrick McKenna.
Ayelet Zurer interpreta a Vittoria Vetra en la película.
Stellan Skarsgård interpreta a Commander Richter en la película.
Pierfrancesco Favino hace el papel de Inspector Olivetti.
Nikolaj Lie Kaas hace el papel de Assassin.
Armin Mueller-Stahl hace el papel de Cardinal Strauss.
Thure Lindhardt interpreta a Chartrand en la película.
David Pasquesi interpreta a Claudio Vincenzi en la película.
Cosimo Fusco hace el papel de Father Simeon.
Victor Alfieri hace el papel de Lieutenant Valenti.
Curt Lowens interpreta a Cardinal Ebner en la película.
Bob Yerkes interpreta a Cardinal Guidera en la película.
Marc Fiorini hace el papel de Cardinal Baggia.
Carmen Argenziano hace el papel de Father Silvano Bentivoglio.
Howard Mungo hace el papel de Cardinal Yoruba.
Rance Howard interpreta a Cardinal Beck en la película.
Steve Franken hace el papel de Cardinal Colbert.
Gino Conforti hace el papel de Cardinal Pugini.
Elya Baskin interpreta a Cardinal Petrov en la película.
Thomas Morris interpreta a Urs Weber en la película.
Jonas Fisch hace el papel de Adrian Bachman.
August Wittgenstein interpreta a Swiss Guardsman en la película.
Ben Bela Böhm interpreta a Swiss Guardsman en la película.
Jeffrey Boehm interpreta a Swiss Guard Blue en la película.
Steve Kehela hace el papel de American Reporter.
Ursula Brooks interpreta a BBC Reporter en la película.
Rashmi hace el papel de British Reporter.
Yan Cui interpreta a Chinese Reporter en la película.
Fritz Michel interpreta a French Reporter en la película.
Maria Cristina Heller interpreta a Italian Reporter en la película.
Rafael Petardi interpreta a Italian Reporter en la película.
Yesenia Adame interpreta a Mexican Reporter en la película.
Kristof Konrad hace el papel de Polish Reporter.
Masasa Moyo interpreta a South African Reporter en la película.
Ed Francis Martin hace el papel de South American Reporter.
Cheryl Howard hace el papel de CERN Scientist.
Endre Hules hace el papel de CERN Scientist.
Norbert Weisser interpreta a CERN Scientist en la película.
Vanna Salviati hace el papel de Protester.
Raffi Di Blasio interpreta a Protester en la película.
Todd Schneider hace el papel de Carabinieri.
Rocco Passafaro interpreta a Carabinieri en la película.
Emanuele Secci hace el papel de Carabinieri.
Anna Katarina hace el papel de Docent.
James Ritz hace el papel de Tourist.
Jose David Acevedo interpreta a Italian Police (uncredited) en la película.
Roy Allen III hace el papel de Cardinal (uncredited).
Victor of Aquitaine hace el papel de Vatican Choir Member (uncredited).
Michael Ark interpreta a CNN Reporter (uncredited) en la película.
John Jason Bailey hace el papel de Swiss Guard Blue (uncredited).
Jerred Berg interpreta a Stem Cell Protestor #2 (uncredited) en la película.
Sally Berman hace el papel de Vatican Square Singer (uncredited).
Yuki Bird interpreta a Scientist (uncredited) en la película.
Anthony Bonaventura interpreta a Vatican Police (uncredited) en la película.
Ciara Bravo hace el papel de Italian Girl (uncredited).
Michael Patrick Breen interpreta a Ukrainian General (uncredited) en la película.
Aidan Bristow interpreta a Conclave Priest #1 (uncredited) en la película.
Christopher Casa hace el papel de Tourist (uncredited).
Patrick Casa hace el papel de Choirboy / Tourist (uncredited).
Pasquale Cassalia hace el papel de Rai Reporter (uncredited).
Jimmy Clabots interpreta a Vatican Choir Member (uncredited) en la película.
Austin Michael Coleman interpreta a Young Funeral Mourner (uncredited) en la película.
Robert Corvin interpreta a U.S. Army General (uncredited) en la película.
Gina D'Acciaro interpreta a Vatican Square Singer (uncredited) en la película.
John Dardenne hace el papel de Swiss Guard Multicolor (uncredited).
William "Will" Daubert interpreta a Priest (uncredited) en la película.
Vincent De Paul hace el papel de Vatican Pall Bearer (uncredited).
Norman Deesing hace el papel de Italian Mourner (uncredited).
Angelique Deuitch interpreta a Tourist (uncredited) en la película.
Paul DiVito interpreta a Priest (uncredited) en la película.
Brant Dorman interpreta a Swiss Guard Blue (uncredited) en la película.
Jonn Faircrest hace el papel de Papal Photographer (uncredited).
Les Feltmate interpreta a Priest (uncredited) en la película.
Amanda Jane Fleming interpreta a Tourist (uncredited) en la película.
David Fletcher interpreta a Protestor #3 (uncredited) en la película.
Gregory George Frank hace el papel de Protester (uncredited).
Nancy Gassner-Clayton interpreta a Vatican Square Singer (uncredited) en la película.
Justin Giddings interpreta a Vatican Choir Member (uncredited) en la película.
Alan Gray interpreta a Greek Patriarch Priest (uncredited) en la película.
Marco Greco interpreta a Fireman (uncredited) en la película.
Roger Groh interpreta a Good Bishop (uncredited) en la película.
Nancy Guerriero hace el papel de Vatican Nun (uncredited).
Martin Harris interpreta a Polish Reporter (uncredited) en la película.
Miriam Harris interpreta a Mourner (uncredited) en la película.
David Hill interpreta a Pantheon Tourist (uncredited) en la película.
Brett Hunt interpreta a Vatican Priest (uncredited) en la película.
Marco Infante interpreta a Italian Mourner (uncredited) en la película.
Christopher Karl Johnson hace el papel de Cardinal (uncredited).
Dave Johnson interpreta a Press Photographer (uncredited) en la película.
Gina Juliet interpreta a Vatican Square Singer (uncredited) en la película.
Slim Khezri interpreta a Vatican Square Gypsy (uncredited) en la película.
Sophiah Koikas interpreta a Tourist (uncredited) en la película.
Michael Laren interpreta a Vatican Choir Singer (uncredited) en la película.
Adrian Lee interpreta a Vatican Square Soloist (uncredited) en la película.
David Michael Lewin hace el papel de Mourner (uncredited).
Maynor Lopez hace el papel de Carabinieri (uncredited).
Jon Lucero interpreta a Vatican Police Officer (uncredited) en la película.
Eder López interpreta a Italian Citizen (uncredited) en la película.
Julie Mabry hace el papel de Protester in Vatican (uncredited).
Les Mahoney interpreta a Hip Priest (uncredited) en la película.
Gary Mandarino interpreta a Mourner (uncredited) en la película.
Albert Marrero Jr. interpreta a News Camerman (uncredited) en la película.
Sandra McCurdy interpreta a Italian Tourist (uncredited) en la película.
Anthony Molinari interpreta a Vatican Guard (uncredited) en la película.
Mary E. Morales interpreta a Vatican Square Soloist (uncredited) en la película.
Sauvion Morkunas interpreta a Flag-bearer (uncredited) en la película.
Manuel Nardi interpreta a Priest (Mr. Grey's Men) (uncredited) en la película.
Sarita Ospina hace el papel de Reporter (uncredited).
Dale Pavinski hace el papel de Carabinieri Captain (uncredited).
David Pearl interpreta a Priest (uncredited) en la película.
Jarrod Robbins hace el papel de Swiss Guardsman (uncredited).
Bertrand Roberson Jr. interpreta a Tourist (uncredited) en la película.
John Robert interpreta a Tourist with Hat (uncredited) en la película.
Franklin Ruehl interpreta a Mourner (uncredited) en la película.
Kelly Ryan hace el papel de Protestor #4 (uncredited).
Dylan Saccoccio interpreta a Carabinieri (uncredited) en la película.
Frank Scozzari interpreta a Vatican Police Officer (uncredited) en la película.
James Seaman hace el papel de Costudi (uncredited).
Keith Shawn interpreta a Vatican Tourist (uncredited) en la película.
Jutta Speidel interpreta a Woman (uncredited) en la película.
Matthew Thane hace el papel de Italian Visitor (uncredited).
Nico Toffoli interpreta a Carabieniere Riot (uncredited) en la película.
James Tumminia interpreta a Vatican Priest (uncredited) en la película.
Julian Vada interpreta a Carabinieri (uncredited) en la película.
Ryan Van de Kamp Buchanan interpreta a The Swiss Guard (uncredited) en la película.
Ernie Ventry hace el papel de Gypsy in Square (uncredited).
Shannon Watson hace el papel de Swiss Guard (uncredited).
Jon Morgan Woodward hace el papel de The American with the Sign (uncredited).
Alfred Molina hace el papel de Narrator (voice).
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