- Jim Varney - Wrangler Bob
- Randi Layne - Alexandra Lowell
- J. Don Ferguson - Dean Witter
- Terry Hobbs - Donald Frump III
- Amy Bryson - Sheryl
- Kathleen Webster - Wendy
- Julie Ridley - Dr. Duran
- Paige Conner - Tracy
- Tom Key - Skinner
- Bruce Evers - Agent Dikworth
- Benji Wilhoite - Sonny
- Walter Franks - Joey
- Tina Goetze - Margie
- Chris Edmonds - Billy Showboat / Party Band
- Ralph Pruitt Vaughn - Artimus
- Muriel Moore - Wrangler Bob's Mama
- Ron Culbreth - Commercial Director
- Jerry Campbell - Cowboy with Indigestion
- Deborah Atkinson - Buxom Blonde in Car
- Victor Varnedoe - Party Band
- Peter Stroud - Party Band
- Hoddy Ridarick - Party Band
- David L. Allen - Party Band
- Neilsen T. Catura - Band Roadie
- Shelia Williamson - Land Shark Victim
- Carlos Allen - Party DJ
- Vickie Fiorentino - Party Bartender
- David Thibodeau - Party Bartender
- Tom Atwater - Federal Agent
- Ben Kaya - Federal Agent
- Joe Hartley - Federal Agent
- Ned Lukens - Federal Agent
- Thomas Jackson - Federal Agent
- Kristin Harrison - Little Girl with Handouts
- Thomas Merdis - Sign Workman
- Paul Parks - Sign Workman
- Don Dalton - Limo Driver
- Daryl A. Math - Sleeping Male in Lab
- Eric Axley - Sleeping Male in Lab
- Emmanuel Platanis - Sleeping Male in Lab
- Mary Jo Basile - Court Reporter
- Harold A. Miller III - Baliff
- Dave Straub - Obnoxious News Reporter
- Stan Wakefield - Cowboy in Commercial
- Jim Basile - Cowboy in Commercial
- Scott B. Sowers - Cowboy in Commercial
- Gene Wakefield - Cowboy in Commercial
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Jan Schütte
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